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Recent research explains the role that autoimmunity plays COVID for prolonged periods And how the immune system plays a role in vaccine side effects. We invite you to learn more about immunity and the coronavirus in this note.

How does autoimmunity affect COVID for prolonged periods?

The study published in New England Journal of Medicine, supports the hypothesis that complex immune responses to SARS-CoV-2 could explain the prolonged effects of COVID-19, which refers to a variety of symptoms that persist for months after infection, as well as serious and rare effects. Side effects of the COVID-19 vaccine.

To understand the topic a little more, it is necessary to explain how autoimmunity works, which is modified when our body comes into contact with a virus, or any other infection, and recognizes the proteins and particles of the virus as invaders. These invaders are known scientifically as antigens. Next, the body attempts to neutralize the invading agents, or antigens, to which it generates antibodies and secondary antibodies, also known as autotyped antibody.

What antibody antibodies are used for?

It should be noted that stereotype-specific antibodies are part of the body’s natural process to regulate and, above all, lower the immune response. However, it can have unexpected negative effects, such as:

  • First-line antibodies neutralize and interfere with the body’s ability to fight persistent infection, as is the case with many COVID-19 patients.
  • They mimic the invading organism and attach to our healthy cells in the same way, causing the same symptoms of infection and attack on our healthy cells.
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Autoimmunity and complications of COVID-19

Another point where autoimmunity plays an important role in COVID-19 is the development of Multiples in various devices. Scientists note that the SARS-CoV-2 spike protein binds to the angiotensin-converting enzyme (ACE2) receptors in our cells, and these receptors are found in the cells of the lung, heart, kidneys, nerves, and brain. So the COVID-19 protein can bind to any receptor in any area of ​​the body and have a major impact on our health.

Moreover, by binding to the ACE2 receptor, it not only suppresses healthy cell function but also releases inflammatory proteins, known as cytokines.

According to study author William J. Murphy, “The findings could be useful, particularly in understanding how to increase the efficacy and duration of protective antibody responses, as well as allowing means to determine whether patients are at risk of an antibody-type response or to develop new therapeutic interventions” .

More about autoimmunity in prolonged COVID

On the other hand, according to research by scientists from the University of Cambridge, the NHS Foundation and Addenbrooke Hospital, autoimmunity in COVID occurs in three scenarios:

  • People with mild or no symptoms show a strong immune response early in the infection.
  • Patients who require hospital care have impaired immune responses or systemic inflammation since symptoms appear.
  • People with persistent abnormalities in immune cells and a change in the body’s inflammatory response are at increased risk of developing COVID in the long term.

According to Paul Lyons, co-lead author of the research and the Cambridge Institute for Therapeutic Immunology and Infectious Diseases, “This finding could have important implications for how the disease is managed, as it suggests that we should start treatment as soon as possible to avoid the immune system causing damage sooner.” Too early, possibly in a preventive manner in high-risk groups that is evaluated and diagnosed before symptoms appear.”

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In addition, patients who reported developing symptoms of illness, such as fatigue, for several months after infection (prolonged COVID) were found to have profound changes in many types of immune cells that often persisted for weeks or even months. Defects resolve at different times depending on the type of cell affected.

This research on autoimmunity in COVID-19 will undoubtedly help scientists better understand how to treat and help patients who continue with the sequelae of the coronavirus, as well as prevent more people from developing serious complications from the disease.

with information from Medical news todayAnd Plus MedicineAnd Research and innovation in the UK, s National Institute of Health.

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